Semaglutide is a revolutionary fat loss medication to use alone, or with your TRT protocol, to lose fat and reach your ideal body weight.
Semaglutide is a revolutionary new weight loss medication that is widely hailed as the most effective fat loss agent on the market. Semaglutide lowers body weight by reducing appetite and hunger, increasing satiety, reducing food cravings, altering food preferences, and reducing energy intake. Semaglutide works by mimicking the action of GLP-1, a naturally occurring hormone that helps to regulate blood glucose levels. By binding to, and activating, the GLP-1 receptor, it stimulates insulin secretion and lowers glucagon secretion when blood glucose levels are high, inducing weight loss. It also controls type 2 diabetes, plus, protects against cardiovascular outcomes in patients with type 2 diabetes and established cardiovascular disease.
In addition to its effects on regulation of energy intake and body weight, semaglutide is associated with delayed gastric emptying, making you feel full longer, maintaining satiety, and reducing appetite. Furthermore, semaglutide acts on centers in the brain to reduce appetite. Actions of semaglutide have been shown to arise from effects on the central nervous system, mediated by GLP‐1 receptors in the hypothalamus and hindbrain. Studies suggest that semaglutide directly activates brain areas that are accessible to the molecule and also causes indirect secondary modulation of neuronal activity in other brain areas, including those involved in appetite regulation, food intake, food preference, reward and meal termination, such as the lateral parabrachial nucleus. A study found that Subcutaneous semaglutide suppressed postprandial appetite, including a reduction in hunger and prospective food consumption, and an increase in satiety and fullness, with participants reporting that they were able to control their eating with less difficulty relative to placebo. Simply put, you won’t get hungry too often, and it is easy to eat significantly less.
Semaglutide is a treatment that would only be taken for a few months at a time. After dropping to an ideal weight, you can cease taking the medication, control your calorie intake, and your weight should not increase. If weight does increase after ceasing the treatment, you can resume the medication at any time to return to your ideal weight.
In conclusion, in adults with obesity, once‐weekly semaglutide suppressed appetite, improved control of eating, reduced the frequency and strength of food cravings, lowered ad libitum energy intake and was associated with clinically meaningful reductions in body weight. Semaglutide is the newest and most effective fat loss drug on the market, and millions of people are losing significant weight on this hormone. Semaglutide is now available in compounded form, making it significantly less expensive and more affordable than name brand semaglutide medications such as Ozempic or Wegovy. The effect of semaglutide 2.4 mg once weekly on energy intake, appetite, control of eating, and gastric emptying in adults with obesity
Source Cited: The effect of semaglutide 2.4 mg once weekly on energy intake, appetite, control of eating, and gastric emptying in adults with obesity Martin Friedrichsen, Astrid Breitschaft, Sayeh Tadayon, Alicja Wizert, Dorthe Skovgaard Diabetes Obes Metab. 2021 Mar; 23(3): 754–762. Published online 2021 Jan 3. doi: 10.1111/dom.14280 PMCID: PMC7898914
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